May 11, 2026
Sinawali Biotechnology Solutions is attending the 2026 TIDES Conference in Boston, MA.
Steve Wolk, Founder and Chief Consultant at Sinawali is co-leading a Pre-conference Workshop:
In Vivo Genome Editing: Targeted Delivery & Large Gene Knock-ins
CRISPR gene editing has the potential to redefine treatment of genetic diseases. In order to reach its full potential, two remaining problems need to be solved: targeted delivery and large gene knock-ins. Targeted delivery means getting the CRISPR machinery very specifically to the organs and cell types of the body that will yield a change to the phenotypic expressions of the disease. Many diseases, however, can be caused by hundreds of different mutations, which would require a large number of different therapeutics for each disease. Once we gain the ability to knock out a mutated exon or gene, and knock in a healthy version, all genetic variants of a disease could, in principle, be treated with a single therapeutic. This workshop will address targeted delivery and large gene knock-ins from the perspective of the current state of the technologies, the clinical trials, and the companies and academic institutions working in the space.
If you're interested in learning more about this workshop, feel free to contact us at sinawalibiotech@gmail.com